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MTN 015

Current Study

An Observational Cohort Study of Women following HIV-1 Seroconversion in Microbicide Trials Sponsors: Division of AIDS, US National Institute of Allergy and Infectious Diseases (NIAID) US National Institutes of Health (NIH) Protocol Summary: MTN-015 is …

MTN

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MTN 016

Current Study

(EMBRACE): HIV Prevention Agent Pregnancy Exposure Registry Sponsors: Division of AIDS, US National Institute of Allergy and Infectious Diseases (NIAID) US National Institutes of Health (NIH) Protocol Summary: EMBRACE is a prospective observational coh …

MTN

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MTN 025 (HOPE)

Current Study

A Phase 3B Open-Label Follow-on Trial to Assess the Continued Safety and Adherence to a Vaginal Ring Containing Dapivirine in Women (HOPE) Sponsors: Division of AIDS (DAIDS) Eunice Kennedy Shriver National Institute of Child Health and Development (NIC …

MTN

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MTN 034 (REACH)

Current Study

Study Title: A Phase 2a Crossover Trial Evaluating the Safety of and Adherence to a Vaginal Matrix Ring Containing Dapivirine and Oral Emtricitabine/Tenofovir Disoproxil Fumarate in an Adolescent and Young Adult Female Population Protocol summary: MTN- …

MTN

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MTN 042 (DELIVER)

Current Study

Study Title: Phase 3b, Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring (VR) and Oral TRUVADA Use in Pregnancy Protocol summary: MTN-042 is a Phase 3b, open-label, multi-site, randomized (2:1 in Cohorts 1-2 and 4:1 in Cohort 3) trial desi …

MTN

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MTN 042B

Current Study

Study Title: Assessing Baseline Pregnancy Outcomes in Sub-Saharan Africa Protocol summary: MTN-042B was a cross-sectional chart review study designed to provide an estimate of pregnancy outcome frequency data (term delivery, preterm delivery, still bir …

MTN

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MTN 043

Current Study

Study Title: Phase 3B, Open-label, Safety and Drug Detection Study of Dapivirine Vaginal Ring and Oral TRUVADA® in Breastfeeding Mother-Infant Pairs Protocol summary: MTN-043 is a Phase 3B, open-label, randomized (3:1), multi-site, mother-infant pair P …

MTN

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MTN 045

Current Study

Study Title: Dual Purpose Prevention (DPP) Product Preferences among Couples Protocol summary: MTN-045 was a cross-sectional study that utilized questionnaires, including a Discrete-Choice Experiment (DCE) and joint decision task, to assess couples’ pr …

MTN

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Phase I Trial of the Topical Microbicide BufferGel

Completed Study

Sponsors: Division of AIDS, US National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health (NIH) Protocol Summary: To evaluate the safety of BufferGel, a spermicidal microbicide that acidifies semen and maintains the pro …

MTN

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HPTN/MTN 035

Completed Study

Phase II/IIb Safety and Effectiveness Study of the Vaginal Microbicides BufferGel and 0.5% PRO2000/5 Gel (P) for the Prevention of HIV Infection in Women Sponsors: Division of AIDS, US National Institute of Allergy and Infectious Diseases (NIAID) Natio …

MTN

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MTN 003 (VOICE)

Completed Study

Safety and effectiveness of Tenofovir 1% Gel,Tenofovir Disoproxil Fumarate Tablet and Emtricitabine/ Tenofovir Disoproxil Fumarate Tablet for the prevention of HIV infection in women Sponsors: Division of AIDS US National Institute of Allergy and Infec …

MTN

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MTN 003D

Completed Study

An Exploratory Study of Potential Sources of Efficacy Dilution in the VOICE Trial Sponsors: Division of AIDS, US National Institute of Allergy and Infectious Diseases (NIAID) US National Institutes of Health (NIH) Protocol Summary: MTN 003D is a qualit …

MTN

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MTN 020 (ASPIRE)

Completed Study

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Phase 3 Safety and Effectiveness Trial of a Vaginal Matrix Ring Containing Dapivirine for the Prevention of HIV-1 Infection in Women (ASPIRE) Sponsors: Division of AIDS, US National Institute …

MTN

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MTN 003B

Completed Study

Bone Mineral Density Substudy to MTN 003 (VOICE) Sponsors: US National Institute of Allergy and Infectious Diseases (NIAID) Division of AIDS (DAIDS) US National Institutes of Health (NIH) Protocol Summary: MTN 003B is a substudy of MTN 003 (VOICE), whi …

MTN

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MTN 032

Completed Study

Assessment of ASPIRE and HOPE Adherence Sponsors: Division of AIDS (DAIDS) National Institute of Allergy and Infectious Diseases (NIAID) Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Institute of Menta …

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