Research by Network

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A5264

Current Study

A Randomized Evaluation of Antiretroviral Therapy Alone or with Delayed Chemotherapy Versus Antiretroviral Therapy with Immediate Adjunctive Chemotherapy for Treatment of Limited Stage AIDS-KS in Resource Limited Settings Sponsors: US National Institut …

ACTG

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A5263

Current Study

A Randomized Comparison of Three Regimens of Chemotherapy with Compatible Antiretroviral Therapy for Treatment of Advanced AIDS-KS in Resource Limited Settings Sponsors: US National Institute of Allergy and Infectious Diseases (NIAID) The National Canc …

ACTG

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A5175

Completed Study

A Phase IV, Prospective, Randomized, Open-Label Evaluation of the Efficacy of Once-Daily PI & Once-Daily Non-NRTI – Containing Therapy Combinations for Initial Treatment of HIV-1 Infected individuals from Resource – Limited Settings (PEARLS) Trial …

ACTG

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A5185s

Completed Study

A Substudy of A5175: Effect of Initial Antiretroviral Treatment on Genital Compartment Virus in Individuals from Diverse Areas of the World Sponsor: US National Institute of Allergy and Infectious Diseases (NIAID) Protocol Summary: A5185s was a substud …

ACTG

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A5199

Completed Study

International Neuropsychological Assessment of Patients Initiating Antiretroviral Therapy in Resource-Limited Settings Sponsors: US National Institute of Allergy and Infectious Diseases (NIAID) US National Institute of Mental Health Summary: A5199 was …

ACTG

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A5190/P1054

Completed Study

Assessment of Safety and Toxicity among Infants Born To HIV-1-Infected Women Enrolled in Antiretroviral Treatment Protocols in Diverse Areas of the World Sponsor: US National Institute of Allergy and Infectious Diseases (NIAID) Protocol Summary: A5190- …

ACTG

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A5199

Completed Study

International Neuropsychological Assessment of Patients Initiating Antiretroviral Therapy in Resource-Limited Settings Sponsors: US National Institute of Allergy and Infectious Diseases (NIAID) US National Institute of Mental Health Summary: A5199 was …

ACTG

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A5208

Completed Study

Optimal Combination Therapy After Nevirapine Exposure (OCTANE) Sponsor: US National Institute of Allergy and Infectious Diseases (NIAID) Protocol Summary: A5208 was a phase III study that comprised of two randomized clinical trials that were conducted …

ACTG

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A5221

Completed Study

A Strategy Study of Immediate Versus Deferred initiation of Antiretroviral Therapy for AIDS Disease-Free Survival in HIV-Infected Persons Treated for Tuberculosis with CD4 Sponsor: US National Institute of Allergy and Infectious Diseases (NIAID) Protoc …

ACTG

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A5225

Completed Study

A Phase I/II Dose-Finding Study of High-Dose Fluconazole Treatment in AIDS-Associated Cryptococcal Meningitis Sponsor: US National Institute of Allergy and Infectious Diseases (NIAID) Protocol Summary: A5225 was a phase I/II dose escalation and validat …

ACTG

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A5234

Completed Study

International Trial of Modified Directly Observed Therapy versus Self-Administered Therapy for Participants with First Virologic Failure on a Non-Nucleoside Reverse Transcriptase Inhibitor-Containing Antiretroviral Regimen Sponsor: US National Institut …

ACTG

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A5265

Completed Study

A Phase III, Open-Label, Randomized, Assessment-Blinded Clinical Trial to Compare the Safety and Efficacy of Topical Gentian Violet to that of Nystatin Oral Suspension for the Treatment of OC in HIV-1 Infected Participants in Non-US Settings Sponsors: …

ACTG

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A5273

Completed Study

Mulitcenter Study of Options for SEcond-Line Effective Combination Therapy (SELECT) Sponsors: US National Institute of Allergy and Infectious Diseases (NIAID) Protocol Summary: A5273 is a phase III, dual-arm, open-label, randomized, non-inferiority stu …

ACTG

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A5274

Completed Study

Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment Regimens Sponsors: US National Institute of Allergy and Infectious Diseases (NIAID) Protocol Summary: A5274 is a randomized, open-label, phase IV strategy trial, where parti …

ACTG

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A5278

Completed Study

Pharmacology Substudies of A5263 and A5264 Sponsors: US National Institute of Allergy and Infectious Diseases (NIAID) The National Cancer Institute (NCI) National Institute on Dental Craniofacial Research (NIDCR) Protocol Summary: A5278 is designed to …

ACTG

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A5282

Completed Study

A Randomized, Phase II Trial to Compare an HPV Test-and-Treat Strategy to a Cytology-based Strategy for Prevention of CIN 2+ in HIV-infected Women Sponsor: US National institute of Allergy and Infectious Diseases (NIAID) Protocol Summary: A5282 is a ra …

ACTG

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